Hi,
Thank you for your post.
Before going any further, I want to know when does this issue occur? By default, Transport Scan Job scans Winmail.dat files for viruses. Exchange uses Winmail.dat files to send them between servers to facilitate replication. If Forefront Security for Exchange Server modifies any of these Winmail.dat files, the public folder replication process will fail. To avoid this from happening, you can set a new DWORD registry key named DoNotScanIPMReplicationMessages to 1, and the Transport Scan Job will not scan IPM replication messages.
Meanwhile, you may refer to this article: http://support.microsoft.com/kb/906002/en-us
Regards,
Regards,
Nick Gu - MSFT