Server2008 R2 - logged on as local admin:
An application that I've used for years is doing this:
My VB app uses "RunMe = shell(notepad.exe)" and Notepad opens just fine
Then "RunMe = Shell("c:\mydir\myapp.exe") and I get an error message stating that I don't have rights to run myapp.exe.
I can take the SAME command and use the Windows Run applet and myapp starts as intended so it is not a user rights issue ... it's an issue where Server 2008 will not let my VB program run another specific program (remember it can run Notepad, Write, Explorer
... )