Outlook Safe not only disables addins but also some of the other features like Toolbar customizations , Exchange Client Extensions, Polling for new mail, Preview Pane, and No custom dictionaries are used.
In this case, try deleting the following files which keep the customized data for your changes in the way Outlook looks(appearance).
Note: You might not be able to find some these files eg: views.dat and thats fine.
If this doesnt Work,
Try "outlook /nopreview". If this works then may be a corrupted message in the Inbox
Backup the registry then remove any outlook addin SUBkeys which are at the
Microsoft is conducting an online survey to understand your opinion of the Technet Web site. If you choose to participate, the online survey will be presented to you when you leave the Technet Web site.