Xlsx File is not open on double click but xls file working on double click in Office Excel 2007


  • Hi,

    We recommend you repair the Office 2007 programs first. This can help to restore the following registry key which affects the behavior of opening .xlsx file:

    If the issue persists, you can compare the same registry key with a known good machine that uses the same OS and Office version. Then correct the key manually.

    Important Before you modify the registry key, please backup the registry.

    Rex Zhang

    Rex Zhang

    TechNet Community Support

    Tuesday, February 14, 2012 9:29 AM