Can you share the code that you are using to open the COM port? Who is the manufacture of the device, what is the model number?
I also suggest that you reach back to the Ethernet to RS232 device manufacturing to see what they have to say.
Also, the forums are moving to a new platform. You should post the question on the new forum there: Microsoft Q & A
Sean Liming - Book Author: Starter Guide Windows 10 IoT Enterprise - www.annabooks.com / www.seanliming.com