Hello Jcofske,
According to your description, I suppose that the issue is most likely caused by the Windows Vista Setup media, would you please test the CD on another computer? If it is really damaged or corrupt, we should first order a replacement disk for the continuous troubleshooting.
If the problem still persists, please following the steps below to narrow downs the issue.
1. Upgrade BIOS to the latest version and then reset it to the default manufacturer settings.
2. Format the computer and clean install Windows Vista.
3. The HDD problem: replace a new disk.
Good Luck!