I does not know about the v-key, but for a RSA key it's simple. You install the appliance, you configure your router to use the appliance as a RADIUS server and after you configure your appliance to check your internal RADIUS hosted into your Windows 2008
It's the big step, but it all depend on your key you will be using. I suggest too to ask the vendor, as for sale like that you usually can talk to a product rep that could help for the design.
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