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Can't open xlsx using Vista and office Pro Plus 2010 RRS feed

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    I'm having issues opening xlsx with MS office pro plus 2010. I have MS Vista. When I click on an xlsx workbook on my desktop, there is only an hourglass that appears and does not open up. I have no issues opening xls workbooks. The Dynamic Data Exchange is unchecked. I've tried reinstalling the office. I've tried repairing the office. Nothing is working. Any suggestions will be tried! Thanks!
    Wednesday, March 14, 2012 6:25 PM

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    Hi,

    According to you description, I would suggest you can empty the following folder and rename the registry key which could affect opening the .xlsx file except the Dynamic Data Exchange option:

    Folder location:
    C:\Users\<username>\AppData\Roaming\Microsoft\Excel\XLSTART

    Registry key:

    Note: After renaming the registry key, please repair Office again to recreate a new key.

    Important
    This method is related to modify the registry. However, serious problems might occur if you modify the registry incorrectly. Therefore, make sure that you do it carefully. For added protection, back up the registry before you modify it. Then, you can restore the registry if a problem occurs. For more information about how to back up and restore the registry, click the following article number to view the article in the Microsoft Knowledge Base:
    322756 (http://support.microsoft.com/kb/322756) How to back up and restore the registry in Windows

    HKEY_CLASSES_ROOT\Excel.Sheet.12


    Sincerely
    Rex Zhang

    Rex Zhang

    TechNet Community Support


    • Edited by Rex Zhang Friday, March 16, 2012 7:13 AM
    • Marked as answer by jycg1212 Friday, March 16, 2012 5:28 PM
    Friday, March 16, 2012 7:12 AM

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    Hi,

    According to you description, I would suggest you can empty the following folder and rename the registry key which could affect opening the .xlsx file except the Dynamic Data Exchange option:

    Folder location:
    C:\Users\<username>\AppData\Roaming\Microsoft\Excel\XLSTART

    Registry key:

    Note: After renaming the registry key, please repair Office again to recreate a new key.

    Important
    This method is related to modify the registry. However, serious problems might occur if you modify the registry incorrectly. Therefore, make sure that you do it carefully. For added protection, back up the registry before you modify it. Then, you can restore the registry if a problem occurs. For more information about how to back up and restore the registry, click the following article number to view the article in the Microsoft Knowledge Base:
    322756 (http://support.microsoft.com/kb/322756) How to back up and restore the registry in Windows

    HKEY_CLASSES_ROOT\Excel.Sheet.12


    Sincerely
    Rex Zhang

    Rex Zhang

    TechNet Community Support


    • Edited by Rex Zhang Friday, March 16, 2012 7:13 AM
    • Marked as answer by jycg1212 Friday, March 16, 2012 5:28 PM
    Friday, March 16, 2012 7:12 AM
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    Thanks for replying back to me regarding this issue. I ended up going in to the registry and renaming it Excel.Sheet.12 which it was not named. As soon as I did that it worked. Thanks again for your input. 

    Jim

    Friday, March 16, 2012 2:47 PM