Did you configure the use of "GlobalRefreshEnabled"?
Open powershell
Type: Get-AppvPublishingServer
Lookat:
GlobalRefreshEnabled : False
GlobalRefreshOnLogon : False
GlobalRefreshInterval : 0
GlobalRefreshIntervalUnit : Hour
You need to have "GlobalRefreshEnabled" on True
ps: The behavoir of the application would change! It would get more interaction with the OS.