A couple of things to try:
1. check in the metabase for the correct settings - metabase.xml is located at %windir%\system32\inetsrv
Each of the following should show a "1" value in the IIS MetaBase.xml:
1,C:\WINDOWS\system32\inetsrv\ssinc.dll,0,SSINC,Server Side Includes
1,C:\WINDOWS\system32\inetsrv\asp.dll,0,ASP, Active Server Pages
2. Try changing the environment variables in system properties from the %userprofiler% location to a fixed location such as 'c:\temp'. Do this for both the TEMP and TMP variables.
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