Hi,
Have you patched your RDS infrastructure with the latest updates ? there are a number of fixes released in updates for UPD's. Also failing that, I would check you network connection to the file share and connections to the file share as you may need to remove
sessions for the users with profiles not released on logoff.
Best regards,
Ryan Mangan
Ryan Mangan | Ryanmangansitblog.wordpress.com | Help keep the forums tidy, if this has helped please mark it as an answer