Hi cnelson7007,
Please check the following things to narrow down this issue.
1. Open the site in other browser, such as Chrome and Firefox. Check if the issue only occurs on the IE.
2. Try to access the site settings page directly via http://<site>/_layouts/15/settings.aspx URL. If you can access the settings page, deactivate the “Minimal Download Strategy”
feature, then check if the issue is resolved.
Best regards,
Linda Zhang
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