Hi there -
You can use the del command. For help on the command, type
del /? or see
http://technet.microsoft.com/en-us/library/cc771049(v=ws.10).aspx
That said, it's generally a good idea not to delete files unless you're 100% sure what they're for and that deleting them won't cause Windows to malfunction. In some cases you may find that Windows will not allow you to delete certain files.
Thanks -
James McIllece