Hi David,
Please refer to this official kb for a hint.
Flight Simulator 2004: The game does not start, the game stops responding, or the game shows the splash screen and then quits unexpectedly when you try to start Flight Simulator 2004 - A Century of Flight:
https://support.microsoft.com/en-us/kb/837195
Besides, I also found several users who had the similar issue as yours, their viewpoints may help you, have a look
flight simulator 2004 won’t run in windows 10:
http://answers.microsoft.com/en-us/windows/forum/windows_10-other_settings/flight-simulator-2004-wont-run-in-windows-10/be8549ef-7e8e-46f1-8999-c1288116127d
If the problem still persists, I’m afraid you may need to connect game manufacturer for further help.
Regards
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