Yes, RapidSSL Wildcard Certificate will work with Windows Server 2012 + WSUS.
But make sure what are your website security requirements.
RapidSSL Wildcard Certificate will only secure the Base-Domain and its unlimited number of sub-domains.
If you are wishing to secure multiple domains, then you need to go with Comodo UCC SSL Certificate (suggested by Microsoft), which will allow you to secure up to 250 domains.