Hi Jericho,
From your description, I'd like to suggest changing how much mail to keep offline via the Account Settings.
If you are using Exchange Account, see the steps below:
(Note: The screenshots are from Outlook for Office 365, the user interface might be different if you are using other versions of Outlook.)
1. Go to File > Account Settings > Account Settings, double click the account.
2. Under Offline Settings, move the slider to a desired amount of time, such as 3 months, or 1 month.

You may refer to
this link for more explanation about this.
If you are using IMAP account, the setting can be found under Mail Settings:

In addition, as regards to reducing the size of OST file, hopefully you may find the article below helpful:
Reduce the size of your mailbox and Outlook Data Files (.pst and .ost)
Regards,
Yuki Sun
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