Try to ask on ASP.NET forums:
http://forums.asp.net/ If you have trouble with VS 2010 Beta1, then you can use
http://forums.asp.net/1206.aspxI am pretty sure that it will work on Vista, I am just not experienced with the setup. ASP.NET forums should be able to help you.
It would be good if you can provide them more info - how did you install IIS/ASP.NET and what exactly doesn't work.
-Karel