"Cannot start Microsoft Outlook"-error


  • I have 2 times within one week received the following error on my laptop:

    Cannot start Microsoft Outlook. Cannot open the Outlook window. The set of folders cannot be opened. The information store could not be opened.

    I have personally experienced this error a few times during the last 6 months, and at our office of 10 people, it happens occasionally on almost every users PC independently. When it happened in the past, I could simply (but annoyingly) remove the current profile and create a new one, hereafter I had to set up the email accounts, signatures and the like from scratch. This was time consuming, but necessary. I scanned the web for permanent solutions without any luck. When running Outlook in safe-made, I could see the dialogue window to create a new profile and start outlook like that.

    Now, over the past week, the above fix does not work. I have tried the below to no avail:

    • Run Outlook.exe /safe (receives the same error, no choose-profile window appears)
    • Run Outlook.exe /resetnavpane (receives the same error)
    • Created a new profile form the control panel (receives the same error when opening outlook afterwards)
    • Run SCANPAST.EXE - does not find any errors in the data
    • Delete the data-files associated to the mailboxes.

    Please not that I run all mailboxes in a non-cached mode, each user has a maximum of 5 mailboxes associated with the profile used, and the total amount of mails on the server for the biggest mailbox is 50GB, again running non-cached.

    The only fix I can find, which is NOT a long term solution, is to completely reinstall office. I am definitely not doing that every week. Any long-term solutions to the above or alternatively, quicker fixes when it occurs?

    Looking forward to hearing from you,


    25 September 2017 7:08

Semua Balasan

  • UPDATE: Running the repair tool from "Apps & features" seems to have fixed the issue, but it still does not seems like a permanent solution.
    25 September 2017 7:39
  • Hi Gundersen,

    >>Running the repair tool from "Apps & features" seems to have fixed the issue

    Which repair tool is it? Is it from Microsoft or a third-party tool?

    Do you have Lync or Skype for Business running on your computer? The same error will pop up when Outlook is in use by another program. Usually, Lync/Skype for Business could integrate into Outlook and then cause this issue. In this case, you may consider to exit Lync/Skype for Business (ensure the process is ended in Task Manager), and then try starting Outlook to see the result. 


    Steve Fan

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    26 September 2017 8:41
  • Start Outlook in safe mode

    1. Choose Start > Run.
    2. Type Outlook /safe, and choose OK.
    3. In the Choose Profiles dialog box, accept the default setting of Outlook and choose OK. 
    4. If prompted, enter your password and choose Accept. 
    5. If Outlook does start in safe mode, then the problem is likely with one of your add-ins. You'll need to disable all of your add-ins before restarting Outlook.
    Disable add-ins 
    1. In the upper-left corner of Outlook, choose File > Options > Add-ins.
    2. At the bottom of the View and manage Office Add-ins, make sure the Manage box shows COM Add-ins, and then choose Go.
    3. As a precaution, when the COM Add-ins listing of your current add-ins opens, do one of the following:
    o Manually record the title of every selected add-in listed under Available Add-ins. 
    o Take a screenshot of the property sheet and save the image to a location of your choice.
    4. After you've captured the titles of the selected add-ins, clear all selected check boxes, and then choose OK. 
    5. Choose File > Exit.
    1. Choose Start > Run, and in the Open box, type Outlook.
    2. In the upper-left corner of Outlook, choose File > Options > Add-ins.
    3. Select the check box next to an add-in you want to re-enable, and then choose OK. 
    4. Repeat all steps until you've re-enabled all of the original add-ins and revealed the source of the error. 
    05 Desember 2017 6:16
  • I had Skype but never used it.  On a whim, I uninstalled it.  The fix seemed to work.
    14 Juni 2018 23:09