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NET framework issues

Question
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Dear Microsoft Community support,
I am a biomedical researcher and in our lab we use an application called
Proteome Discoverer by THERMO.To run, this application need to communicate with a server but due to net framework errors the connection is stopped and the application too.
I have this problem with both windows7 and windows8.1.
A similar error appear with another similar application.
Each time the error are the following:
Log Name: Application
Source: Application Error
Date: 20/09/2017 02:02:33
Event ID: 1000
Task Category: (100)
Level: Error
Keywords: Classic
User: N/A
Computer: st16
Description:
Faulting application name: mscorsvw.exe, version: 4.7.2053.0, time stamp: 0x58fa6b78
Faulting module name: clr.dll, version: 4.7.2114.0, time stamp: 0x59a63e48
Exception code: 0xc0000005
Fault offset: 0x0000000000304378
Faulting process id: 0x1018
Faulting application start time: 0x01d331a3bb3e2b32
Faulting application path: C:\Windows\Microsoft.NET\Framework64\v4.0.30319\mscorsvw.exe
Faulting module path: C:\Windows\Microsoft.NET\Framework64\v4.0.30319\clr.dll
Report Id: 000e808d-9d97-11e7-8262-901b0e372dfd
Faulting package full name:
Faulting package-relative application ID:
Event Xml:
<Event xmlns="http://schemas.microsoft.com/win/2004/08/events/event">
<System>
<Provider Name="Application Error" />
<EventID Qualifiers="0">1000</EventID>
<Level>2</Level>
<Task>100</Task>
<Keywords>0x80000000000000</Keywords>
<TimeCreated SystemTime="2017-09-20T00:02:33.000000000Z" />
<EventRecordID>3952</EventRecordID>
<Channel>Application</Channel>
<Computer>st16</Computer>
<Security />
</System>
<EventData>
<Data>mscorsvw.exe</Data>
<Data>4.7.2053.0</Data>
<Data>58fa6b78</Data>
<Data>clr.dll</Data>
<Data>4.7.2114.0</Data>
<Data>59a63e48</Data>
<Data>c0000005</Data>
<Data>0000000000304378</Data>
<Data>1018</Data>
<Data>01d331a3bb3e2b32</Data>
<Data>C:\Windows\Microsoft.NET\Framework64\v4.0.30319\mscorsvw.exe</Data>
<Data>C:\Windows\Microsoft.NET\Framework64\v4.0.30319\clr.dll</Data>
<Data>000e808d-9d97-11e7-8262-901b0e372dfd</Data>
<Data>
</Data>
<Data>
</Data>
</EventData>
</Event>
Log Name: Application
Source: .NET Runtime
Date: 20/09/2017 02:02:33
Event ID: 1023
Task Category: None
Level: Error
Keywords: Classic
User: N/A
Computer: st16
Description:
Application: mscorsvw.exe
Framework Version: v4.0.30319
Description: The process was terminated due to an internal error in the .NET Runtime at IP 00007FF818814378 (00007FF818510000) with exit code 80131506.
Event Xml:
<Event xmlns="http://schemas.microsoft.com/win/2004/08/events/event">
<System>
<Provider Name=".NET Runtime" />
<EventID Qualifiers="0">1023</EventID>
<Level>2</Level>
<Task>0</Task>
<Keywords>0x80000000000000</Keywords>
<TimeCreated SystemTime="2017-09-20T00:02:33.000000000Z" />
<EventRecordID>3951</EventRecordID>
<Channel>Application</Channel>
<Computer>st16</Computer>
<Security />
</System>
<EventData>
<Data>Application: mscorsvw.exe
Framework Version: v4.0.30319
Description: The process was terminated due to an internal error in the .NET Runtime at IP 00007FF818814378 (00007FF818510000) with exit code 80131506.
</Data>
</EventData>
</Event>
how can i solve this problem?
thanks
dds
Monday, September 25, 2017 1:32 PM
All replies
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Hi,
Did the another similar application crash randomly or can’t run?
Did you run the Proteome Discoverer successfully on Windows 7/8.1 before this issue occur?
If no, please confirm with the application’s vender to make sure it’s supported on your current version of Windows 7/8.1.
Please try to run the System File Checker tool (SFC.exe) to check system files and recovery corrupted files, here are steps:
1. Open Command Prompt (as administrator).
2. Type sfc /scannow, and then press Enter.
Please remember to mark the replies as answers if they help.
If you have feedback for TechNet Subscriber Support, contact tnmff@microsoft.com.- Proposed as answer by Vera Hu Thursday, September 28, 2017 1:47 PM
Tuesday, September 26, 2017 9:26 AM -
Hi,
How’s everything going? Please feel free to give me any update.
Please remember to mark the replies as answers if they help.
If you have feedback for TechNet Subscriber Support, contact tnmff@microsoft.com.Friday, October 13, 2017 1:24 AM