Run the typical eseutil /d on the database dismount the DB to perform the offline defrag. Once complete, you need to manually re-seed. It's typically discouraged to run offline defrags unless you'll be gaining a considerable amount of disk space and you're
willing to for go the down time. It's typically better to create a new DB set up the SCR replica and move the mailboxes to the new DB then delete the old DB.
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