No, that doesn't make sense. BitLocker is something enabled on a specific instance of Windows and protected to that specific instance using hardware on the system hosting that instance. It's not something the WIM image format can even capture (because a
WIM image is a file based image format). Even if you were to use a bit-based image format (which I highly recommend against) you would be capturing an encrypted blob protected by a key stored on another system. Finally, I don't think sysprep will even run
on a BitLocker protected system and yes, syspreping a reference system to create a reference image is required for any imaging.
Enabling BitLocker during OS deployment using the OSD feature set in ConfigMgr (this is a ConfigMgr forum) or MDT is pretty straight-forward though. I would highly encourage you to deploy MBAM first though to provide BitLocker and BitLocker key management.
Jason | https://home.configmgrftw.com | @jasonsandys