Thank you for your posting in Windows Server Forum.
For your issue, you can delete the cached copy of roaming profile by GPO setting. Please check the GPO setting “Computer Configuration | Administrative Templates | System | User Profiles
| Delete cached copies of roaming profiles.”
More information. User Profiles
To manually remove you can also use registry setting. If you’re connecting to a remote computer and not cleaning up a local registry, click on Registry in the File menu and select Connect To Network Registry. Enter the name of the computer you deleted profiles
from and browse down in the registry to these two locations:
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